T rainee Name : Supervisor ( s ) : Structured tr ct : Title : Intradialytic Exercise Preconditioning and the Effect on Myocardial Stunning
نویسنده
چکیده
Introduction: Cardiovascular disease (CVD) has been well documented as the leading cause of death in the general population worldwide. Physical activity is a modifiable factor in the development and progression of CVD reducing its incidence by 42-44% and reducing mortality and hospital admissions. The presence of chronic kidney disease (CKD), and the recurrence of cumulative circulatory stress caused by hemodialysis (HD) increases the risk of CVD, myocardial stunning, morbidity and mortality. The effect of intradialytic exercise on myocardial stunning is unknown.
منابع مشابه
Cardioprotection Acquired Through Exercise: The Role of Ischemic Preconditioning
A great bulk of evidence supports the concept that regular exercise training can reduce the incidence of coronary events and increase survival chances after myocardial infarction. These exercise-induced beneficial effects on the myocardium are reached by means of the reduction of several risk factors relating to cardiovascular disease, such as high cholesterol, hypertension, obesity etc. Furthe...
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Late preconditioning (PC) against myocardial stunning develops after coronary artery occlusion (CAO) at rest and subsequent reperfusion. We investigated whether late PC occurs after exercise-induced ischemia (high-flow ischemia) in dogs. A circumflex coronary artery stenosis (by using occluders) was set up before the onset of treadmill exercise in nine chronically instrumented dogs to suppress ...
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BACKGROUND The mechanism through which ischemic preconditioning causes cardioprotection is unknown. The present study investigated the role of stunning in preconditioning. METHODS AND RESULTS We studied three different protocols of preconditioning: two cycles of 2-minute ischemia separated by 5-minute reperfusion (2'PC), one cycle of 5-minute ischemia by 5-minute reperfusion (5'PC1), and two ...
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